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. Does Rogaine Work? On Thin Hair, Hair Loss, and More - Healthline. Minoxidil, the key active ingredient in Rogaine, has been available on the market for hair loss for more than three decades, since the introduction of 2% formula in 1986.This popular hair loss .. Minoxidil: Side Effects, Dosage, Uses, and More - Healthline minoxidil. Minoxidil oral tablet is a generic drug that lowers blood pressure by relaxing and enlarging certain blood vessels. It can cause serious side effects such as chest pain, heart function problems, and salt and water retention. Learn about its warnings, interactions, and how to use it safely.. Minoxidil (Topical Route) Side Effects - Mayo Clinic. Minoxidil can stain clothing, hats, or bed linen if your hair or scalp is not fully dry after using the medicine. Avoid transferring the medicine while wet to other parts of the body minoxidil. This can occur if the medicine gets on your pillowcase or bed linens or if your hands are not washed after applying minoxidil. To apply minoxidil topical foam:. Minoxidil and its use in hair disorders: a review - PMC minoxidil. Minoxidil was first introduced as an antihypertensive medication and the discovery of its common adverse event, hypertrichosis, led to the development of a topical formulation for promoting hair growth minoxidil. To date, topical minoxidil is the mainstay treatment for androgenetic alopecia and is used as an off-label treatment for other hair loss .